Airways Obstruction and Uneven Gas Distribution in the Lung

Airways obstruction and uneven gas distribution in the lung.

Lung fluid exchange after uneven pulmonary artery obstruction in sheep.

We studied steady state transvascular fluid and protein exchange after uneven obstruction of the pulmonary arteries. In anesthetized sheep, ventilated by positive pressure, we measured pulmonary artery and left atrial pressures, cardiac output, lung lymph flow, and lymph/plasma protein ratios. We calculated pulmonary vascular resistance. In 16 sheep we obstructed the pulmonary arteries with var...

Physical signs of diffuse airways obstruction and lung distension.

The following are physical signs which can be elicited in patients with chronic airways obstruction: a reduction in the length of the trachea palpable above the sternal notch; tracheal descent with inspiration; excessive use of the scalene and sternomastoid muscles; excavation of the suprasternal and supraclavicular fossae during inspiration; jugular venous filling during expiration; loss of bu...

Gas mixing and distribution in the lung.

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Airways obstruction in rheumatoid arthritis.

Owing to the report of an association between rheumatoid arthritis (RA) and obliterative bronchiolitis we have determined the prevalence of airflow obstruction in unselected patients with RA and normal chest radiographs. Spirometry was performed on 100 patients with rheumatoid arthritis and 84 control subjects matched for age, sex, and smoking habits. Patients with rheumatoid arthritis had sign...